产品货号：
Z19745
中文名称：
Livin/BIRC7抗体
英文名称：
Anti-Livin/BIRC7 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Livin/BIRC7 Antibody |
| 指标别名 | BIRC7;KIAP;LIVIN;ML IAP;MLIAP;RING finger protein 50;RNF50 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | BIRC7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Livin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Livin.The immunogen is located within the last 50 amino acids of Livin. |
| 计算分子量 | 33kDa |
| 成分 | Livin Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Livin Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis,or programmed cell death,is related to many diseases,such as cancer.Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins.IAP proteins form a conserved gene family that binds to and inhibits cell death proteases.A novel member in the IAP protein family was recently identified and designated Livin and KIAP for kidney IAP.Livin/XIAP contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-alpha and Livin-beta.Transfection of Livin in cells resulted in protection from apoptosis induced by FADD,BAX,RIP,RIP3 and DR6.Livin has direct interaction with several caspases including caspase-3,-7,and -9.Livin inhibits the activation of caspase-9 induced by Apaf-1,cytochrome c,and dATP.The two isoforms of Livin appear to have different functions and tissue distributions. |
| Uniprot ID | Q96CA5 |
| 基因名全称 | Baculoviral IAP repeat-containing 7 |
| 蛋白名全称 | Baculoviral IAP repeat-containing 7 |
| 推荐稀释比 | Livin antibody can be used for detection of Livin by Western blot at 0.5μg/mL.A band at 33kDa can be detected.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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